The AGRE pedigree catalog currently contains 1354 pedigrees, including 1074 multiplex families. All families had blood collected from at least one parent and siblings affected with an autism spectrum disorder. Additionally, ADIs were completed for every family and additional phenotypic data were collected.



These data and genetic samples are available to approved AGRE researchers.

Summary of Data Available To Researchers (July 2011 Catalog)

Total number of pedigreed families (Multiplex and Simplex)
(Includes pedigree pictures, ADI-R computer-scored diagnostic classifications, and blood on at least one affected child and one parent)		 1354
Total number of affected individuals 2695
  Male 2129
  Female 566
Total number of Simplex Families 280
Total number of Multiplex Families 1074
Total number of families with blood samples 1354
Total number of families with ADI-R data 1354
Total number of families with ADOS data 1114
Total number of families with Vineland data 919
Total number of families with Raven’s, PPVT and/or Stanford-Binet data 1080
Total number of families with Physician Visits 362
Total number of families with Race and Ethnicity Information 1285
Total number of families with Fragile X testing 1351
Total number of families with Full Mutation Fragile X 6
Total number of families with at least one member genotyped 995
Number of affected individuals per family (may include MZ twins):
Families with two affected individuals 965
Families with three affected individuals 141
Families with four affected individuals 21
Families with five affected individuals 5
Twin Family Pedigrees 247
  Dizygotic 170
  Monozygotic 76
Triplet Family Pedigrees 11
Quadruplet Family Pedigrees (Monozygotic) 1

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