The AGRE pedigree catalog currently contains 1736 pedigrees, including 1271 multiplex families. All families had blood collected from at least one parent and siblings affected with an autism spectrum disorder. Additionally, ADIs were completed for every family and additional phenotypic data were collected.



These data and genetic samples are available to approved AGRE researchers.

Summary of Data Available To Researchers (October 2012 Catalog)

Total number of pedigreed families (Multiplex and Simplex)
(Includes ADI-R computer-scored diagnostic classifications and blood on at least one affected child and one parent)
1736
Total number of affected individuals 3348
  Male 2641
  Female 707
Total number of Simplex Families 465
Total number of Multiplex Families 1271
Total number of families with blood samples 1736
Total number of families with ADI-R data 1736
Total number of families with ADOS data 1377
Total number of families with Vineland data 1165
Total number of families with Raven’s, PPVT and/or Stanford-Binet data 1427
Total number of families with Physician Visits 359
Total number of families with Race and Ethnicity Information 1667
Total number of families with Fragile X testing 1734
Total number of families with Full Mutation Fragile X 6
Total number of families with at least one member genotyped 1007
Number of affected individuals per family (may include MZ twins):
Families with two affected individuals 1135
Families with three affected individuals 189
Families with four affected individuals 19
Families with five affected individuals 8
Twin Family Pedigrees 323
  Dizygotic 204
  Monozygotic 118
Triplet Family Pedigrees 15
Quadruplet Family Pedigrees (Monozygotic) 1

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